Huperzine A extract

Huperzine A extract

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•Product name: Huperzine A extract
•Also known as: Haboyin;Hupzine A;Kimpukan A;HUPERIZINE
•Product code: NFA0198
Botanical source: Lycopodium serratum Thunb.
•CAS No.: 102518-79-6
•Active ingredient:Huperzine A
•Certifications: ISO, HACCP, CQC, KOSHER
•Specification: 1.0%, 98.0% Synthesized
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Product Details

Product Instruction

◆ Huperzine A extract is a natural plant alkaloid extracted from the traditional Chinese medicine Huperzia spp., Which is a powerful, reversible and highly selective second-generation acetylcholinesterase inhibitor with a slightly yellow to white crystalline appearance. Powder, easily soluble in chloroform, soluble in methanol and ethanol, slightly soluble in water, has high fat solubility, small molecules, can penetrate the blood-brain barrier well, and is distributed more in the frontal lobe of the brain after entering the center , Temporal lobe, hippocampus and other brain areas that are closely related to learning and memory, have a strong inhibitory effect on acetylcholinesterase (AchE) at low doses, and significantly increase the content of acetylcholine (Ach) in the synaptic space in the distribution area. thereby enhancing the excitatory conduction of neurons, enhancing the excitement of learning and memory brain regions, and improving the cognitive function, enhancing memory retention and promoting memory reproduction. It is currently the most successful drug developed for treating Alzheimer's disease (Alzheimer's disease) in China.

 

Specification of Huperzine A 1.0% Natural

DESCRIPTION

SPECIFICATIONS

ANALYSIS/METHOD

Characters

Powder

Qualified [Organoleptic]

Color

Brown yellow fine powder

Qualified [Organoleptic]   

Odour

Characteristic

Qualified [Organoleptic]

Mesh

80

100% pass 80 mesh [CP2010]

Loss on drying

Ash

≤5.0%

≤5.0%

3.82% [CP2010]

3.67 [2g/525℃/3hrs]

Identification:


Positive    

Content %(Method: HPLC)



Huperzine-A

≥1.0%

1.01% [CP2010]

Heavy Metals(Method: AAS)

≤10ppm

Qualified [CP2010]

Pb                         

≤1ppm

Qualified [GB/T 5009.12-2003]

As

≤1ppm

Qualified [GB/T 5009.11-2003]

Hg

≤0.1ppm

Qualified [GB/T 5009.15-2003]

Cd

≤1.0ppm                       

Qualified [GB/T 5009.17-2003]

Microbiological



Total Plate Count

1000cfu/g Max

<100cfu/g [AOAC990.12,16th]

Yeast&Mold

100cfu/g Max

<50cfu/g [AOAC996.08, 991.14]

E.Coli colonies/g

Negative

Negative [AOAC2001.05]

Samonella colonies/g  

General Status

GMO Free

Non-Irradiation

Negative

 

Complies

Complies

Negative [AOAC990.12]

 

Complies

Complies

 

Product benefits

◆ Huperzine A extract is used to treat and improve the memory dysfunction of middle-aged and elderly people, improve the associative memory function; to reduce the memory caused by excessive use of the brain, and improve the efficiency of learning and work;

◆ Huperzine A powder is used for neurasthenia accompanied by memory loss;

◆ Huperzine A is used for memory loss caused by cerebrovascular disorders;

◆ Huperzia Serrata Extract is used to improve the memory of senile dementia, and has obvious effects on improving and restoring patients' cognitive, memory function and improving emotional behavior abnormalities;

◆ Natural Huperzine-A powder is used to treat myasthenia gravis;

◆ It has an improving effect on associative disorders, cognitive impairment, memory loss, etc. associated with schizophrenia;

◆ It can also improve memory function associated with various brain diseases and somatic diseases.

 

Product application

◆ Huperzine A extract is a new drug currently used to treat benign memory disorders. It can effectively prevent cerebral neurasthenia in middle-aged and elderly people, restore cerebral nerve function, activate brain neurotransmitters, and can also affect the free radical system, reduce somatostatin, intracellular [Ca2 +], and glutamic acid content, and increase calmodulin. (CaM) and calmodulin messenger ribonucleic acid (CaMmRNA) expression levels and other pharmacological mechanisms to improve cognitive function and learning and memory.

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