Product Instruction
◆ Methyl 3,4,5-trimethoxybenzoate is an organic compound with a molecular formula of C11H14O5. It is prepared by the methylation reaction of gallic acid and dimethyl sulfate. Used as a pharmaceutical intermediate, it is the main raw material of the anxiolytic drug trimetazine and the gastrointestinal drug trimebutine maleate.
Specification Methyl 3,4,5-trimethoxybenzoate 99.0%
ITEMS | SPECIFICATIONS | METHOD/STANDARD |
DESCRIPTION | ||
Characters | Powder | Organoleptic |
Color | White to off white crystalline | Organoleptic |
Odour | Characteristic | Organoleptic |
Coloration at 5% methanol solution (in 380nm) | ≤0.2 | -- |
Acidity content | ≤0.5% | -- |
Assay | ≥99.70% | HPLC |
Impurities | Total ≤ 3000ppm | HPLC |
ATMB ≤ 2000ppm | HPLC | |
TMBA ≤ 500ppm | HPLC | |
TMBE ≤ 500ppm | HPLC | |
Unknown impurities ≤ 250ppm | HPLC | |
Sulfuric ashes | ≤0.1% | -- |
Melting point | 80.0-85.0℃ | -- |
Loss on drying | ≤0.5% | -- |
Impurity content by TLC | No impurities in 366nm | -- |
Identification TLC | The sample and the control had the same ratio of the shift | -- |
Waters | ≤0.4% | -- |
Product benefits
◆ Methyl 3,4,5-trimethoxybenzoate is an intermediate of the antibacterial synergist trimethoprim. Use
◆ It is the main raw material of the anxiolytic drug trimetazine, the gastrointestinal drug trimebutine maleate, etc.
Product application
◆ Used as an intermediate of antibacterial synergist trimethoprim.
◆ Used as a pharmaceutical intermediate, it is the main raw material of the anxiolytic drug trimetazine, gastrointestinal drug trimebutine maleate
