Fucoidan and Cancer Instruction
◆ kombu is natural medicine which extracted from seaweed including Fucus, kelp and wakame, Laminaria japonica, etc. It contains special components with anti-coagulant, lower blood fat, anti-tumor and anti-HIV functions.
◆ By fucoidan pharmacy, pharmacology and toxicology systematic study and completed Phase II clinical trials, researchers found mozuku has good efficacy on treatment of nephrotic syndrome, early and midterm chronic renal failure, especially for improving renal function and reduce serum creatinine effect.
Product components
◆ Sulfated polysaccharide is a unique chemical composition in alginate. As one kind of water-soluble miscellaneous polysaccharide, it is consist of L- fucose-4-sulfate, as well as a small amount of galactose, mannose, xylose, glucose, arabinose, uronic acid, protein, potassium, sodium, calcium, magnesium and other metal ions. Structure L- fucose-4-sulfate is poly-1,2-junctioned α-L- pyran fucose and sulfate are mainly in the C-4 position of the hydroxyl group.
Specification of Fucoidan 85.0%
ITEMS | SPECIFICATIONS | METHOD/STANDARD |
Characters | Powder | Organoleptic |
Color | Off white to light yellow | Organoleptic |
Odour | Characteristic | Organoleptic |
Mesh | 80~100 | Mesh 80 |
Solubility | Soluble in water | In-House |
pH | 4.5~7.5 | SC/T 3404-2012 |
Loss on drying | ≤10.0% | SC/T 3404-2012 |
Ash | ≤32.0% | SC/T 3404-2012 |
Fucose | ≥15.0% | SC/T 3404-2012 |
Organic (SO4)2- | ≥15.0 | SC/T 3404-2012 |
Free (SO4)2- | Negative | -- |
Identification: | By UV/TLC | |
Assay (On dry basis) | Fucoidan≥85.0% | SC/T 3404-2012 |
Heavy Metals | ≤10ppm | GB/T 5009.12-2003 |
Pb | ≤1ppm | GB/T 5009.11-2003 |
As | ≤2ppm | GB/T 5009.15-2003 |
Hg | ≤0.3ppm | GB/T 5009.17-2003 |
Cd | ≤0.2ppm | GB/T 5009.12-2003 |
Microbiological | ||
Total Plate Count | 1000cfu/g Max | AOAC990.12,16th |
Yeast&Mold | 100cfu/g Max | AOAC996.08, 991.14 |
E.Coli colonies/g | Negative (-) | AOAC2001.05 |
Samonella colonies/g | Negative (-) | AOAC990.12 |
Fucoidan and Cancer Benefits
◆ Fucoidins have been investigated in preclinical studies for anti-oxidant, cognitive protective, anti-inflammatory, anti-angiogenic, anti-cancer, anti-viral, and anti-hyperglycemic activity.
Product Application
◆ It can be applied in health food field, food additives industry, which can be added into the dairy, beverage, health care products, pastries, cold drinks, bread, milk and so on.
◆ Brown seaweed extract can be applied in cosmetic field, which is a kind of water-soluble polymer natural extracts with sntiphlogistic sterilization effect. So it can be used as a new type of high moisturizing instead of glycerin.
◆ Laminaria japonica Fucoidan can be applied in pharmaceutical field, which is the raw material of new tradition medicine added in kidney products.
Applicable group of Fucoidan and Cancer
◆ Low immunity group; Nephrotic syndrome and early, midterm chronic renal failure patients; High blood sugar, high blood lipids group; Cancer prevention and the early and mid-term cancer patients; Chemotherapy group.
Recommend dosage
◆ 250~350mg in health food; 0.15% in food additive.
Flow chart of Laminaria japonica extract fucoidan
