Griffonia Seed Extract

Griffonia Seed Extract

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•Product name: Griffonia seed extract 5-HTP 98.0%HPLC
•Also known as: 5-HTP, Griffonia simplicifollia extract
•Product code: YG-BLA021
•Botanical source: Griffonia simplicifollia
•5-HTP CAS No.: 56-69-9;114-03-4
•Formula: C11H12N2O3
•Active Ingredient: DL-5-Hydroxytryptophan
•Certifications: ISO, HACCP, CQC, KOSHER, HALAL
•Specification: 5-HTP 25.0%, 98.0%HPLC
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Product Details

Product Instruction

◆ 5-hydroxytryptophan is an amino acid substance. It can be used as a precursor of serotonin (serotonin, 5-HT) in the human body (and then as a precursor of melatonin). Griffonia seed extract can increase the concentration of serotonin in the brain, improve depression and promote the formation of melatonin, improve sleep quality, and suppress appetite, but these studies still have problems. 

◆ Griffonia seed extract are rich in 5-hydroxytryptophan and are currently the main natural source for the manufacture of 5-HTP. 5-hydroxy-D-tryptophan is classified as a pharmaceutical ingredient in some countries. In the United States, the United Kingdom, and Canada, it is considered a dietary supplement (health supplement). 

 

Specification of 5-HTP 98.0%HPLC

ITEMS

SPECIFICATIONS

METHOD/STANDARD

Characters

Powder

Organoleptic

Color

White to off-white

Organoleptic 

Odour

Characteristic

Organoleptic

Mesh

80

--

Loss on drying

≤2.0%

5g/105℃/2hrs

Ash

≤1.0%

2g/525℃/3hrs

Benzo(a)pyrene

≤10ppb

EP

Sum PAH 4

≤50ppb

EP

Identification:


By HPLC/TLC

Assay

5-HTP (Dry Basis) ≥98.0%

HPLC

Heavy Metals

≤10ppm

USP

Pb   

≤2ppm

ICP-MS

As

≤1ppm

ICP-MS

Hg

≤0.1ppm

ICP-MS

Cd

≤1.0ppm 

ICP-MS

Microbiological



Total Plate Count

1000cfu/g Max

USP

Yeast&Mold

100cfu/g Max

USP

E.Coli colonies/g

Negative (-)

USP

Samonella colonies/g

Negative (-)

USP


Griffonia Seed Extract Benefits

◆ Griffonia simplicifollia seed extract and Anxiety. Low serotonin levels can lead to abnormal anxiety. With HTP, there is a good chance for serotonin to go back to its natural level, so you can feel normal again.

◆ 5-hydroxy-D-tryptophan and Weight Loss. If you would like to lose weight, Griffonia seed extract may do wonders for you as well. An appetite too healthy may be caused by low serotonin levels. Taking in 5-HTP can normalize these levels. At the same time, 5-htp supplements can decrease your food intake by creating a feeling of fullness. It also is able to increase the secretion of the hormone leptin (an appetite regulator) thus resulting to enhanced weight loss.

◆ Natural sourced 5-hydroxy-D-tryptophan and Bipolar Disorder. Clinical studies have shown the anti-depressant effect of 5HTP supplement for those suffering from bipolar II disorder. It can alleviate and reduce to improve the general quality of life of bipolar sufferers.

◆ Powdered Griffonia simplicifollia seed extract and Fibromyalgia. One of the major benefits  is the help that it gives for people with fibromyalgia. It helps improve sleep while at the same time reduce depression, pain, stiffness and anxiety - all of which are symptoms of this condition.

◆ Botanical extract and Headaches. 5-hydroxytryptophan supplement has also been used for treating chronic headaches such as tension headaches, juvenile headaches and migraine. These are conditions which may be related to low serotonin.  Ithas the ability to reduce the severity and frequency of these conditions, with fewer side effects compared to other chronic headache medications.

 

Product application

◆ 5-hydroxy-D-tryptophan can be used as raw materials of drugs for anti-bacterial, anti-depressants, anti-tumor and sedation.

◆ It is widely used in fields of pharmaceutical and health products. 

◆ 5-Hydroxy-DL-tryptophan can be used as insomnia, other similar symptoms of psychasthenia and lose weight product raw material.

◆ It is widely used in health products industry; It can be used as dietary supplements increased therapeutic function, it is wide used in field of dietary.

◆ Supplement products; 5-Hydroxy-DL-tryptophan can be used as products of sedative and anti-bacterial, they are widely used to add to beauty product in cosmetic industry.

 

Recommended dosage

Further research is needed to determine the optimal human dose of Griffonia simplicifolia. The lowest effect dose for rats is 25mg/kg of bodyweight, which is about 4mg/kg of Griffonia simplicifolia extract, assuming 20% 5-Hydroxy-DL-tryptophan content. This translates to following human doses:

◆ 275mg Griffonia(55mg of 5-HTP) for a 150lb person

◆ 350mg Griffonia (70mg of 5-HTP) for a 200lb person

◆ 450mg Griffonia (90mg of 5-HTP) for a 250lb person

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