Anti-photoaging effect of panax ginseng extract ginsenosides on skin

- Dec 12, 2019-

◆ Skin aging includes natural aging caused by genetic factors and / or force majeure factors and photoaging caused by environmental factors, mainly ultraviolet light. Ginseng has a unique and extensive medicinal value, contains many biologically active substances, and its main active ingredient is ginsenoside.

mechanism of Skin aging panax ginseng ginsenosides

◆ Ginsenosides have the effects of improving human immunity, promoting metabolism, anti-tumor, anti-fatigue, anti-light aging, anti-oxidation, scavenging free radicals and immune stimulating effects. Ginseng extract can antagonize cell DNA damage caused by reactive oxygen species and prevent UV Formation of skin tumors.

Dried Panax ginseng root

◆ The main cause of skin photoaging is ultraviolet light. Photoaging skin can up-regulate the expression of many cellular regulatory factors such as interleukin, matrix metalloproteinase, nuclear factor-κB, and activated protein (AP-1) in the body. At the same time, the content of collagen and antioxidant enzymes that protect the skin is reduced, which causes the skin exposed to ultraviolet light to become pigmented, increase wrinkles, loose and loose capillaries.: A mixture of ginseng and hawthorn promotes the expression of type Ⅰ collagen At the same time, reduce the secretion of MMP-1. The mixture of ginseng and hawthorn inhibits the formation of wrinkles and increases the moisture of the skin to slow down aging. The expression of MMP-1 and MMP-3 in dermal fibroblasts was significantly reduced after ginsenoside Rd treatment, indicating that ginseng exerts its function of regulating fibroblast metabolism by affecting the expression of MMP-1 and MMP-3 in fibroblasts. .

Chemical structure panax ginseng extract ginsenosides

◆ Ginsenosides can reduce lipid peroxide (LPO) and malondialdehyde by increasing the activity of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px) in the body. Aldehyde (MDA) content, etc. to achieve the function of delaying aging.