Theafl avins (TFs) was discovered by Roberts E.A.H. in 1957. It is a kind of substance which is soluble in ethyl acetate and is orange-yellow formed by oxidative condensation of tea polyphenols. . Theaflavins are the key ingredients that promote the bright color of black tea soup. They are also an important ingredient influencing the taste and freshness of tea soup. Theaflavins also have anti-oxidation, anti-bacterial, anti-viral, anti-inflammatory, anti-tumor and anti-cardiovascular diseases. And other pharmacological activities.
◆ Scavenging free radicals and antioxidants
Oxidation catechins of Theaflavins have strong antioxidant activity and can act as free radical scavengers and metal chelators.
Theaflavins inhibit tumor growth and proliferation. Theaflavins also inhibit tumor metastasis and spread.
The anticancer and anticancer effects of theaflavins are mainly achieved by antioxidation, inhibition of cancer cell growth, promotion of cancer cell apoptosis, and resistance to chromosome breakage.
◆ Anti-inflammatory and immune regulation
Theaflavin has been widely reported for its regulation of immune response and potential anti-inflammatory activity, and its molecular mechanism of anti-inflammatory has gradually become clear with its in-depth study of its anti-inflammatory effects.
◆ Antibacterial and antiviral
Theaflavins have inhibitory effects on various bacteria, and have been found so far, including Bacillus botulinum, Enterobacter, Staphylococcus aureus, Clostridium, Bacillus cereus, Shigella, and cariogenic bacteria, and The crude TF is stronger than the single TF. Theaflavins also have antiviral activity and are even potent against some stubborn viruses that cause headaches in the medical world, such as SARS  and HIV-1.
◆ Anti-cardio-cerebral vascular disease
Theaflavins have the effects of protecting the heart muscle, regulating blood lipids, relaxing blood vessels and resisting atherosclerosis.
◆ Regulate nerve function
Theaflavins are involved in the regulation of a variety of neurological functions and are associated with a variety of neurological diseases, such as Alzheimer's disease, Parkinson's disease, and the like.
Theaflavins can reduce allergic reactions in the skin and the like.
◆ Radiation resistance
Theaflavins BTF1 and BTF2 have an effect on the light loss caused by UVB irradiation.
◆ Other effects
Theaflavins can reduce the synthesis of extracellular matrix by regulating the p38MAPK signal transduction pathway, delaying diabetic glomerular hypertrophy and glomerular sclerosis. Theaflavins have a certain effect on alleviating the acute I/R injury of the fatty liver. Theaflavins can reduce the steatosis, oxidative stress, inflammation and hepatocyte apoptosis of the fatty liver.
Black tea theaflavins 40.0%hplc
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