The active ingredients of Salvia miltiorrhiza or extract mainly include fat-soluble and water-soluble. Its pharmacological effects include anti-tumor, prevention and treatment of cardiovascular diseases, anti-inflammatory, anti-oxidation, chemotherapeutic sensitization, liver protection and other pharmacological effects (anti-depression, neuroprotection, immune regulation, etc.).
The active ingredients of Salvia miltiorrhiza are mainly divided into two major factors: fat solubility and water solubility.
◆ 1. 1 More than 50 fat-soluble ingredients have been isolated from the fat-soluble ingredients.
Mainly including orthoquinones and guanidines, such as tanshinone I, tanshinone IIA, tanshinone IIB, cryptotanshinone, tanshinone V, tanshinone VI, dihydrotanshinone I, isotanshinone I, cryptotanshin, danshenxin, and purple ginseng , B, A and so on. Studies have shown that these ingredients have anti-tumor, anti-inflammatory, radiochemical sensitization, neuroprotection, anti-cardiovascular disease and other effects.
◆ 1. 2 Water-soluble components have been isolated from Salvia miltiorrhiza.
More than 20 water-soluble components have been isolated.Mainly phenolic compounds such as caffeic acid, danshensu, rosmarinic acid, methyl rosinate, salvianolic acid, and dansolic Acid G, raw lithospermic acid and salvianolic acid D, salvianolic acid A, salvianolic acid C, salvianolic acid L, lithosperic acid and esterified derivatives thereof; salvianolic acid B, lithospermic acid B and its salts and esters Chemical derivatives, salvianolic acid E; less sugar compounds such as glucose, galactose, fructose, raffinose and the like. Studies have shown that these ingredients have anti-tumor, anti-depression, inhibition of inflammatory response, anti-coagulation, dilatation of coronary artery and so on.
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