Tongkat Ali (Eurycomalongifolia), also known as Malaysian ginseng, native ginseng, natural Viagra, etc., is a plant of the genus Eurycoma of Simaroubaceae, mainly distributed in Southeast Asian countries such as Indonesia, Vietnam, and Malaysia. In addition to its significant effects in improving male sexual function, Tongkat Ali and its extracts also have lowering blood sugar, anti-cancer, lowering blood pressure, lowering blood uric acid levels in rats with hyperuricemia, and alleviating pathological damage to kidney tissue. And other pharmacological effects.
1. Improve sexual function
Geali can improve the anti-fatigue ability of male rats, and can effectively reduce the effect of high-intensity exercise on rat serum testosterone. Dongge Aligan extract quakenone can inhibit the production of estradiol in the testes and promote the production of testosterone steroids.
2. Hypoglycemic function
In tongkat ali, alkaloids such as 9-hydroxy iron excretion meterone can inhibit the Wnt signaling pathway, and then play a role in lowering blood sugar.
3. Anti-cancer function
The bitter lignin compounds in Tongkat Ali can inhibit the proliferation of human prostate cancer cells LNCaP. Tongkat Ali's methanol extract can induce the apoptosis of leukemia cells K-562, and it appears to be dose-dependent.
4. Antihypertensive function
Tongkat Arigen extract can relax blood vessels by inhibiting angiotensin type 1 receptor and angiotensin converting enzyme and enhancing angiotensin type 2 receptor and bradykinin activity.
5. Other pharmacological functions
Tongkat Ali extract can reduce blood uric acid levels in hyperuricemia rats caused by adenine, yeast extract and potassium oxazinate. Among them, ethanol extract can also effectively relieve pathological damage of kidney tissue. Anti-osteoporosis, anti-proliferative, anti-malarial, antibacterial, anti-rheumatic and anti-ulcer functions.