Ep Standard CAS 520-27-4 Diosmin

Ep Standard CAS 520-27-4 Diosmin

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•Product name: Diosmin EP8.0
•Also known as: diosmetin 7-O-rutinoside, venosmine
•Molecular: C28H32O15
•CAS Number: 520-27-4
•Product code: YG-PA013
•Botanical source: Citrus limon (L.) Burm
•Certifications: ISO, HACCP, CQC, KOSHER, HALAL, GMP
•Specification: Diosmin EP8.0, Diosmin 90.0%~102.0%, Diosmin:Heperidin 90:10
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Product Details

Strong technical strength, the use of scientific production management methods, and the selection of high-quality materials are the guarantee of our high-quality Ivy leaf powder extract, Echinacea purpurea extract in cosmetics hs code, Aloe vera gel freeze dried powder. Since the establishment, our company has consistently adhered to the quality policy of 'relying on science and technology, strict management, meticulous manufacturing, and striving for first-class'. Our company has a modern vision, we take the market as the guide, take customer satisfaction as the direction of enterprise development.

Diosmin Powder Instruction

◆ venosmine is a semi-synthetic flavonoid, a derivative of hesperidin. It is used to treat various vascular diseases including acne, varicose veins, poor leg circulation (venous stasis) and bleeding from the eye or gums (bleeding). It is also used to prevent liver toxicity. It is usually mixed with hesperidin. 

◆ There are extensive clinical trials that show diosmin improves all stages of venous disease including venous ulcers and improves quality of life. pure diosmin is currently a prescription medication in some European countries, containing 90% venosmine and 10% hesperidin, and sold as a nutritional supplement in the United States.

 

Specification of Diosmin EP8.0

ITEMS

SPECIFICATIONS


METHOD/STANDARD

DESCRIPTION




Characters

Powder


Organoleptic

Color

A grayish-yellow or light-yellow hygroscopic powder.


 

Organoleptic 

Odor

Characteristic


Organoleptic

Solubility

 

Practically insoluble in water soluble in aqueous   alkaline sol.


 

In-House

Substances

Impurity A (Acetoisovanillone)≤1%


EP8.0


Impurity B (Hesperidin) ≤5%


EP8.0


Impurity C (Isorhoifolin) ≤3%


EP8.0


Impurity E (Linarin) ≤3%


EP8.0


Impurity F (Diosmitin) ≤3%


EP8.0


Any other impurity≤1%


EP8.0


Total of other impurities and impurity A≤1%


EP8.0


Total   impure≤10%


EP8.0

Water

≤6.0%


EP8.0

Sulphated   ash

≤0.2%


EP8.0

Methanol

≤3000ppm


EP8.0

Pyridine

≤200ppm


EP8.0

Identification:



By   HPLC/TLC

Assay

90.0%~102.0%


HPLC

Heavy   Metals

≤10ppm


EP8.0

Pb 

≤1ppm


EP8.0

As

≤2ppm


EP8.0

Hg

≤0.1ppm


EP8.0

Cd

≤1.0ppm 


EP8.0

Microbiological




Total   Plate Count

1000cfu/g   Max


EP8.0

Yeast&Mold

100cfu/g   Max


EP8.0

E.Coli   colonies/g

Negative   (-)


EP8.0

Samonella   colonies/g

Negative   (-)


EP8.0


Diosmin Powder Benefits

◆ Resistant to inflammation and hyper susceptibility.

◆ Resistant to bacterium, include epiphyte and bacteria etc.

◆ Compared with other flavone plant, orange flavone has it own unique physiologic functions.

◆ Resistant to oxidation activity, includes to clear away single turn oxygen, peroxide, hydroxide radical and other free radical.

◆ Prevent circulatory system to be harmed by ill, make capillary vessel more flexible, resist platelet aggregation and regulate cardiovascular.

 

Product Application

◆ As a natural antioxidant, Diosmin Powder is mainly used in cosmetic industry.

◆ As a natural antioxidant, it is widely used in health product and food industry.

◆ As a raw material of drugs for lowering cholesterol, anti-virus and anti-inflammatory, it is mainly used in pharmaceutical field.

 

Citrus extract and derivatives series products

No.

Product Name

Specification

1

Diosmin

>90.0%

2

Hesperidin

>90.0%

3

Hesperidin Methyl Chalcone

>90.0%

4

Methyl Hesperidin

>94.0%

5

Hesperitin

>95.0%

6

Diosmetin

>98.0%


We vigorously promote the enterprise spirit of 'dedication, innovation, quality, and efficiency', increase scientific research and development, and implement harmonious and humanized management. Products enjoy a high reputation in the Ep Standard CAS 520-27-4 Diosmin field. Wish we have a pleasant and long terms business together!!! Our company effectively controls our business risk and financial risk, and can continuously improve our profitability.
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