Aloe Emodin CAS 481-72-1 Instruction
◆ Aloe-emodin is a hydroxyanthraquinone present in Aloe vera leaves, has a specific in vitro and in vivo antineuroectodermal tumor activity. Easily soluble in hot ethanol, ether, benzene, the solution is yellow, but also soluble in ammonia solution and sulfuric acid, the solution is crimson. Aloeemodin has anti-inflammatory, anti-inflammatory and healing effects on damaged skin. Now it is widely used as raw material for medicine and cosmetics.
◆ The cytotoxicity mechanism consists of the induction of apoptosis, whereas the selectivity against neuroectodermal tumor cells is founded on a specific energy-dependent pathway of drug incorporation. Its pharmacodynamic experiments show that it can significantly improve the left ventricular ejection fraction and short-axis shortening rate of animal models of acute myocardial ischemia, and has a significant protective effect against myocardial ischemia; at the same time, aloe-emodin can also reverse hyperlipidemia animals The QT interval of the heart caused by the model is prolonged and has potential anti-arrhythmic effects.
Specification of Aloe emodin 95.0%
Items | SPECIFICATIONS | METHOD/STANDARD |
DESCRIPTION | ||
Characters | Powder | Organoleptic |
Color | Yellow-red | Organoleptic |
Odor & Taste | Light bitter | Organoleptic |
Solubility | Slightly soluble in ethanol | -- |
Loss on drying | ≤2.0% | -- |
Residue on Ignition | ≤0.1% | -- |
Melting point | 220~223℃ | -- |
Identification: | By HPLC/TLC | |
Assay (On dry basis) | ≥95.0% Aloe emodin | HPLC |
Heavy Metals | ≤10.0ppm | CP2010 |
Pb | ≤1.0ppm | CP2010 |
As | ≤2.0ppm | CP2010 |
Hg | ≤0.1ppm | CP2010 |
Cd | ≤1.0 ppm | CP2010 |
Microbiological | ||
Total Plate Count | 1000cfu/g Max | CP2010 |
Yeast&Mold | 100cfu/g Max | CP2010 |
E.Coli colonies/g | Negative (-) | CP2010 |
Samonella colonies/g | Negative (-) | CP2010 |
Aloe Emodin CAS 481-72-1 Benefits
◆ Anti-tumor activity: One of the mechanisms of action is to inhibit the biosynthesis of DNA, RNA and protein of cancer cells, thereby inhibiting the proliferation and growth of cancer cells;
◆ Antibacterial activity: Mainly manifested in the inhibition of Staphylococcus, Streptococcus, Diphtheria, Bacillus subtilis, anthrax, Paratyphoid bacillus, Shigella. (effective concentration is 1.5 ~ 25mg / ml);
◆ Laxative effect: clinically used as a laxative, it has an appetite and large intestine laxative effect (stimulation of intestinal smooth muscle motility), and has special effects on constipation and acne;
◆ Immunosuppressive effect: this powder can inhibit the production of antibodies in organisms;
◆ Skin wound repair;
◆ Other effects: lipid-lowering effect, make hair soft and shiny, easy to relax, anti-dandruff, protect teak from termites;
Product application
◆ Pharmaceutical and chemical intermediates Aloe Emodin CAS 481-72-1, dye intermediates (various aromatic derivatives for the production of dyes and organic pigments);
◆ Health Food Additives: (Compound) Capsule (300mg/Particle Aloe Vera Dry Powder, Vitamin C) Detox Capsule, Soft Capsule (1000mg/granule, of which aloeemodin contains 10mg).
◆ Cosmetic raw materials and hair care raw materials: mainly use the antibacterial and anti-inflammatory and skin wound repair effects of this product ( seaweed mask, cream, hydrating cosmetics, etc.)