Pharmaceutical Grade Diosmin CAS 520-27-4 with High Quality

Pharmaceutical Grade Diosmin CAS 520-27-4 with High Quality

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•Product name: Diosmin EP8.0
•Also known as: diosmetin 7-O-rutinoside, venosmine
•Molecular: C28H32O15
•CAS Number: 520-27-4
•Product code: YG-PA013
•Botanical source: Citrus limon (L.) Burm
•Certifications: ISO, HACCP, CQC, KOSHER, HALAL, GMP
•Specification: Diosmin EP8.0, Diosmin 90.0%~102.0%, Diosmin:Heperidin 90:10
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Product Details

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Diosmin Powder Instruction

◆ venosmine is a semi-synthetic flavonoid, a derivative of hesperidin. It is used to treat various vascular diseases including acne, varicose veins, poor leg circulation (venous stasis) and bleeding from the eye or gums (bleeding). It is also used to prevent liver toxicity. It is usually mixed with hesperidin. 

◆ There are extensive clinical trials that show diosmin improves all stages of venous disease including venous ulcers and improves quality of life. pure diosmin is currently a prescription medication in some European countries, containing 90% venosmine and 10% hesperidin, and sold as a nutritional supplement in the United States.

 

Specification of Diosmin EP8.0

ITEMS

SPECIFICATIONS


METHOD/STANDARD

DESCRIPTION




Characters

Powder


Organoleptic

Color

A grayish-yellow or light-yellow hygroscopic powder.


 

Organoleptic 

Odor

Characteristic


Organoleptic

Solubility

 

Practically insoluble in water soluble in aqueous   alkaline sol.


 

In-House

Substances

Impurity A (Acetoisovanillone)≤1%


EP8.0


Impurity B (Hesperidin) ≤5%


EP8.0


Impurity C (Isorhoifolin) ≤3%


EP8.0


Impurity E (Linarin) ≤3%


EP8.0


Impurity F (Diosmitin) ≤3%


EP8.0


Any other impurity≤1%


EP8.0


Total of other impurities and impurity A≤1%


EP8.0


Total   impure≤10%


EP8.0

Water

≤6.0%


EP8.0

Sulphated   ash

≤0.2%


EP8.0

Methanol

≤3000ppm


EP8.0

Pyridine

≤200ppm


EP8.0

Identification:



By   HPLC/TLC

Assay

90.0%~102.0%


HPLC

Heavy   Metals

≤10ppm


EP8.0

Pb 

≤1ppm


EP8.0

As

≤2ppm


EP8.0

Hg

≤0.1ppm


EP8.0

Cd

≤1.0ppm 


EP8.0

Microbiological




Total   Plate Count

1000cfu/g   Max


EP8.0

Yeast&Mold

100cfu/g   Max


EP8.0

E.Coli   colonies/g

Negative   (-)


EP8.0

Samonella   colonies/g

Negative   (-)


EP8.0


Diosmin Powder Benefits

◆ Resistant to inflammation and hyper susceptibility.

◆ Resistant to bacterium, include epiphyte and bacteria etc.

◆ Compared with other flavone plant, orange flavone has it own unique physiologic functions.

◆ Resistant to oxidation activity, includes to clear away single turn oxygen, peroxide, hydroxide radical and other free radical.

◆ Prevent circulatory system to be harmed by ill, make capillary vessel more flexible, resist platelet aggregation and regulate cardiovascular.

 

Product Application

◆ As a natural antioxidant, Diosmin Powder is mainly used in cosmetic industry.

◆ As a natural antioxidant, it is widely used in health product and food industry.

◆ As a raw material of drugs for lowering cholesterol, anti-virus and anti-inflammatory, it is mainly used in pharmaceutical field.

 

Citrus extract and derivatives series products

No.

Product Name

Specification

1

Diosmin

>90.0%

2

Hesperidin

>90.0%

3

Hesperidin Methyl Chalcone

>90.0%

4

Methyl Hesperidin

>94.0%

5

Hesperitin

>95.0%

6

Diosmetin

>98.0%


We take Pharmaceutical Grade Diosmin CAS 520-27-4 with High Quality that cater to and meet the needs of customers as our responsibility, and we have an independent research and development department to continuously introduce new ones. Our continuous growth is the direct result of our ability to offer products and services that meet and exceed international standards, which allows our clients to be more satisfied. They're durable modeling and promoting well all over the world.
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