Pharmaceutical Intermediate CAS 633-65-8 97% 98% Phellodendron Extract Powder Berberine Hydrochloride

Pharmaceutical Intermediate CAS 633-65-8 97% 98% Phellodendron Extract Powder Berberine Hydrochloride

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•Product name: Berberine hcl 98.0%
•Also known as: Berberine, berberine hcl powder, Phellodendron extract
•Product code: YG-PA001
•Botanical source: Phellodendron amurense
•CAS No.: 633-65-8
•Active ingredient: Berberine hcl
•Certifications: ISO, HACCP, CQC, KOSHER
•Specification:97.0% Titration, 90.0%HPLC, CP2010, CP2015
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Product Details

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Berberine HCl CAS 633-65-8 Instruction

◆ Natural Berberine, an important alkaloid, which can be extracted from plants like berberine, cork, and three needles. It has a remarkable bacteriostatic effect. With richful berberine hcl, the commonly used berberine hydrochloride is also called berberine hcl extract. 

Phellodendron amurense bark extract berberine hcl

 Berberine is an important alkaloid that can be extracted from plants such as Coptis chinensis, Phellodendron chinense, and Berberis virgetorum. It has significant antibacterial effect. The commonly used berberine hydrochloride is also called berberine hydrochloride. Berberine can resist pathogenic microorganisms, and it can inhibit a variety of bacteria such as dysentery bacillus, tuberculosis bacilli, pneumococcus, typhoid bacillus, and diphtheria bacillus, among which the bacterium has the strongest effect on dysentery bacillus, which is commonly used to treat bacterial gastroenteritis and dysentery Waiting for digestive diseases. Clinically, it is mainly used to treat bacterial dysentery and gastroenteritis. It has no drug resistance and side effects.

 Berberine hcl chemical structure

Specification of Berberine hcl CP2010

ITEMS

SPECIFICATIONS

METHOD/STANDARD

Characters

Powder

Organoleptic

Color

Yellow or Orange powder

Organoleptic

Extract solvent

Ethanol & Water

--

Loss on drying

≤12.0%

CP2010

Residue on Ignition

≤0.2%

CP2010

Cyanide

None

CP2010

Organic nitrile

None

CP2010

Bulk Density

50-60g/100ml

--

Solvent Residue

Eur.Pharm

--

Pesticide Residue

Negative

--

Identification:


By HPLC/TLC/Titration

Assay (On dry basis)

≥90.0% Berberine hcl

HPLC


≥97.0% Berberine hcl

Titration

Heavy Metals

≤10.0ppm

CP2010

Pb   

≤1.0ppm

CP2010

As

≤1.0ppm

CP2010

Hg

≤0.1ppm

CP2010

Cd

≤0.2ppm 

CP2010

Microbiological



Total Plate Count

1000cfu/g Max

CP2010

Yeast&Mold

100cfu/g Max

CP2010

E.Coli colonies/g

Negative (-)

CP2010

Samonella colonies/g

Negative (-)

CP2010


Product benefits

 Berberine HCl CAS 633-65-8 has an obvious hypolipidemic effect: Clinical observations show that in patients with hypercholesterolemia treated with berberine, total cholesterol, cholesterol, low-density lipoprotein and triglyceride decreased by 20% after oral administration of berberine for 3 months ~ 28%.

 Phellodendron extract has a hypoglycemic effect: Diabetic patients take 0.4 g orally 4 times a day, after taking 1 to 3 months, it may reduce blood sugar to normal levels.

how the benefits of berberine make it possible

 Other benefits of Berberine extract.

Berberine's antihypertensive effect is also very good: most elderly patients with hypertension can take their blood pressure to a normal range after taking this medicine. This is because berberine in berberine can directly act on vascular smooth muscle and has a vasodilator effect.


Berberine HCl CAS 633-65-8 Application

Berberine has been used as an over-the-counter drug in the treatment of diarrhea in clinic, but modern pharmacological studies have confirmed that berberine has significant anti-heart failure, anti-arrhythmia, lower cholesterol, anti-vascular smooth muscle proliferation, improve insulin resistance, anti-platelet, anti-inflammatory And other functions, so it may have broad and important application prospects in cardiovascular system and nervous system diseases, which are increasingly valued.

 

Recommended dosage

 For diabetes: 0.9 to 1.5 grams of berberine hcl daily, 2-4 months.

 For high cholesterol: 0.6 to 1.5 grams of berberine hcl daily, 2-12 months.

 For high blood pressure: 0.9 grams of berberine hcl daily, 2 months.


Manufacturing process


Berberine hcl CAS 633-65-8 flow chart


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